Manchester City face an away trip to League One leaders Wigan in the fifth round of the FA Cup, while Chelsea host struggling Championship side Hull City.
The Premier League leaders beat Cardiff City 2-0 on Sunday to set up a tie with Paul Cook’s side, who have a two-point lead at the top of English football’s third tier.
Meanwhile, Manchester United will travel to take on the winner of Tuesday’s fourth round replay between Birmingham and Huddersfield, and Tottenham, should they beat Newport on Wednesday, will face either Rochdale or Millwall.
Result of FA Cup 5th Round Draw:
Sheffield Wednesday vs Notts County/Swansea
West Brom vs Southampton
Chelsea vs Hull City
Leicester vs Sheffield United
Huddersfield/Birmingham vs Man Utd
Millwall/Rochdale vs Newport/Spurs
Brighton vs Coventry
Wigan vs Man City